Lactylation as a metabolic-epigenetic switch in cancer: dual roles in cell death resistance and therapeutic vulnerability

Nature·Mar 6

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1

The glycolysis-lactylation axis: a metabolic-epigenetic driver of immunosuppression and therapy resistance in cancer

Frontiers·Mar 23

2

p300: expanding beyond acetylation to mastermind lactylation-dependent tumorigenesis

Frontiers·Mar 31

3

Histone lactylation-driven feedback loop modulates pyrimidine metabolism to promote oral carcinogenesis

Nature·Mar 19

4

Targeting metabolic-epigenetic-immune axis in cancer: molecular mechanisms and therapeutic implications

Nature·Jan 26

5

Role of lactylation-induced macrophage failed phenotypic switching in sustaining inflammation of diabetic wounds

Frontiers·Feb 23

6

Lactylation in cancer biology: Unlocking new avenues for research and therapy - Hou - 2025 - Cancer Communications

Wiley Online Library·Aug 19

7

Lysine lactylation in diseases: beyond histone lactylation

Nature·Nov 24

8

Lactate-mediated histone lactylation promotes melanoma angiogenesis via IL-33/ST2 axis

Nature·Oct 6