Novel MYC-driven medulloblastoma models from multiple embryonic cerebellar cells

Nature·May 15

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Researchers have developed novel models of MYC-driven medulloblastoma from multiple embryonic cerebellar cells. These models are being used to study the biology of medulloblastoma, including its transcriptional regulation, epigenetic modifications, and metabolic reprogramming. The studies aim to identify potential therapeutic vulnerabilities and opportunities in the treatment of this pediatric brain tumor.

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