Stabilization of FASN by USP5-mediated deubiquitination promotes hepatocellular carcinoma progression
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Research suggests that the stabilization of FASN, potentially through deubiquitination by various USP proteins, may play a role in the progression of certain cancers, including hepatocellular carcinoma. The involvement of different USP proteins and pathways in cancer progression is indicated, although the specific mechanisms and relationships between these factors are not entirely clear. The stabilization of FASN appears to be a common thread in the progression of various types of cancer, including liver and gastric cancer.
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