USP13 deubiquitinates and stabilizes cyclin D1 to promote gastric cancer cell cycle progression and cell proliferation

Nature·Jun 13

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Research suggests that certain deubiquitinases play a role in promoting cancer progression in various types of cancer, including gastric cancer. The specific mechanisms and enzymes involved appear to vary, with some studies implicating USP13, USP14, and other deubiquitinases in the stabilization of key proteins such as cyclin D1. The relationship between deubiquitination and cancer progression is complex, with different enzymes and pathways potentially involved in different cancer types.

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Frontiers·Oct 24

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Nature·May 15

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Nature·Oct 21

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Nature·Aug 13

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Nature·Mar 2

View original report at Nature ↗

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