miRNA-133 augments coelomocyte phagocytosis in bacteria-challenged Apostichopus japonicus via targeting the TLR component of IRAK-1 in vitro and in vivo | Scientific Reports

Nature·Jul 30

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Research on aquatic animals, including Apostichopus japonicus, has identified various non-coding RNAs that play a role in enhancing coelomocyte phagocytosis in response to bacterial challenges. These non-coding RNAs, such as miRNA-133 and circRNA432, appear to target different components of immune response pathways. The specific mechanisms and targets of these non-coding RNAs are being studied, with some research focusing on their role in regulating phagocytosis in different species, including oysters.

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circRNA432 enhances the coelomocyte phagocytosis via regulating the miR-2008-ELMO1 axis in Vibrio splendidus -challenged Apostichopus japonicus

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