Research is exploring the role of NRF2 in cancer, particularly its implications for immunotherapy and therapeutic targeting. Studies are investigating various aspects of NRF2, including its involvement in metabolism, genome integrity, and the tumor immune microenvironment, as well as its potential as a target for precision medicine and immunotherapy strategies. The relationship between NRF2 and other factors, such as KEAP1 and epigenetic modifications, is also being examined for its potential to improve cancer treatment outcomes.