The MYC-dependent lncRNA MB3 inhibits apoptosis in Group 3 Medulloblastoma by regulating the TGF-β pathway via HMGN5 | Cell Death & Disease

Nature·Nov 6

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Research has identified a role for the MYC-dependent lncRNA MB3 in inhibiting apoptosis in Group 3 Medulloblastoma by regulating the TGF-β pathway. Other studies have explored the involvement of various genes and pathways in medulloblastoma and neuroblastoma, including MYC, NPM1, and the HIF-1α and p53 pathways. The specific mechanisms and interactions involved in these processes are being investigated, with some research suggesting that long non-coding RNAs like MEG3 may also play a regulatory role in certain pathways.

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View original report at Nature ↗