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HealthJaved Anees · CC0
Science & Technology

India’s first dengue vaccine arrives with a crucial safety caveat

India's first dengue vaccine, Qdenga, has arrived but with a crucial safety caveat. In children who have never been infected with dengue, the vaccine could simulate a primary infection, offering protection against DENV-1 and DENV-2 but not DENV-3 — and could thereby enhance a later dengue infection, making prior screening important.

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India's first dengue vaccine, and its serotype-specific safety limitation, is a science-and-health highlight.

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Key facts

  • India's first dengue vaccine is Qdenga.
  • Risk of enhancing dengue in children not previously infected.
  • Protects against DENV-1 and DENV-2 but not DENV-3.

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